Findings challenge the traditional view that antimicrobial resistance (AMR) emerges from pathogens that acquire new mutations. Samples from ICU patients suggest that instead, highly diverse pathogen communities harbor pre-existing resistant genotypes. The results suggest that interventions aimed at limiting the spread of bacteria between patients may provide a powerful approach to combat AMR.
Scientists contest longstanding hypothesis about mysterious illness affecting Gulf War veterans, providing first direct evidence that symptoms are driven by impaired mitochondria.
A team has reported on the rapid generation of new fluorinated molecular fragments for drug discovery using organocatalysis.
Walter Chiapponi, who has been creative director of the Italian luxury shoemaker since 2019, will leave the company after the presentation of his latest collection at Milan Fashion Week on September 22.
PGA Tour Commissioner Jay Monahan returns to work next week and some top players believe he has to regain their trust after leaving members in the dark over an about-face deal with the Saudi Arabia wealth fund behind LIV Golf.
PGA Tour Commissioner Jay Monahan returns to work next week and some top players believe he has to regain their trust after leaving members in the dark over an about-face deal with the Saudi Arabia wealth fund behind LIV Golf.
It is stated that the automotive and timber industries, as well as air travel, are far from recovering
Prostate cancer is a leading cause of death among American men, and it's resistant to one of the most powerful chemotherapy medications -- cisplatin. Now, researchers have developed the first therapy of its kind that disrupts prostate cancer cells' metabolism and releases cisplatin into the weakened cells, causing them to die. In mouse models, an orally administered version shrunk tumors substantially.
Leprosy has existed since at least Biblical times, yet scientists still don't know exactly how Mycobacterium leprae causes the disease's symptoms. Though antibiotics can treat the illness, researchers are concerned about the increase in drug-resistant strains. Now, a team has begun to understand the unique role certain immune receptors play in leprosy infections in mice, which could lead to new types of treatments for this disease and others in humans.
It goes without saying, but breakfast is honestly the most important meal of the day. What you put in your body first thing in the morning can totally set the tone for how you feel for the rest of the day. As such, you want a breakfast that’s full of protein which means one thing: […]
A freight train carrying industrial chemicals derailed near East Palestine, Ohio, in February 2023, and to avoid explosions, authorities conducted a controlled release and burned the cars' contents. Residents were worried about their health and the environment, so researchers have been assessing the local air quality with stationary and mobile sampling methods. Now they report that some gases, including acrolein, reached levels that could be hazardous.
Yuzvendra Chahal will soon be travelling to West Indies to take part in the ODIs an T20Is leg of the tour. Meanwhile, Dhanashree is planning her grand comeback after recovering from knee injury.
Meet your new favorite device, which one reviewer literally calls "heaven for my eyeballs."
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If you didn't file your 2019 tax return, the deadline to claim your refund is approaching. Here's what to know.
New research show the need for an international effort to limit global pollution by PFAS. The substance inhibits the immune system and can, thus, increase the risk of infections and cancer, and PFAS can reduce the effect of vaccination programs against e.g. tetanus, diphtheria, influenza and COVID-19.
Two councils and a resident are seeking a legal challenge against the Home Office’s plans to house asylum seekers on airfields.
The six-week abortion ban replaces an earlier ban that is currently being blocked by a judge's order.
Upset over poor drainage system that resulted in waterlogging in Bhatia village due to flash flood, a woman allegedly slapped Jannayak Janta Party (JJP) MLA Ishwar Singh on Wednesday.
In this episode of Business Matters, we discuss what will happen to supply chains that took decades to perfect and will availability of critical materials itself become a challenge.
"Succession," HBO's family drama that wrapped in May, leads the nominations for the 75th Primetime Emmy Awards announced Wednesday.
Nothing exists in a vacuum, but physicists often wish this weren't the case. If the systems that scientists study could be completely isolated from the outside world, things would be a lot easier. Take quantum computing. It's a field that's already drawing billions of dollars in support from tech investors and industry heavyweights including IBM, Google and Microsoft. But if the tiniest vibrations creep in from the outside world, they can cause a quantum system to lose information.
Researchers have demonstrated that a transplant surgical procedure (called 'needle trauma') triggers a profound immune response and causes the death of most grafted dopamine neurons. They also found that co-transplantation of neuronal cell therapy with host regulatory T cells resulted in effective suppression of needle trauma and significant improvement in the survival and recovery of grafts. These findings suggest a path for the 'realistic' use of cell therapy to treat neurodegenerative disorders.
In efforts to support Germany’s energy transition agenda, P&O Maritime Logistics will use its Multi ...
Like their viral cousins, retrotransposons have been found borrowing the cell's own machinery to achieve their goals. They hijack a little-known piece of the cell's DNA repair function to close themselves into a ring-like shape and then create a matching double strand. The finding upends 40 years of conventional wisdom and may offer new insights into cancer, viral infections and immune responses. It could also offer a new way to insert sequences into the genome.