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Новости за 04.04.2024

Telling the story of the opioid crisis: A narrative analysis of the TV series Dopesick

Plos.org 

by Joel Piqué-Buisan, Josep-E Baños, Irene Cambra-Badii

Dopesick (2021) is the first TV series whose plot deals exclusively with the opioid crisis in the United States. The current study uses narrative analysis and framing theory to explore this series, discussing its portrayal of the people and themes involved in the opioid crisis. Our analysis found that although Dopesick attempts to portray multiple dimensions of the opioid crisis, its narrative oversimplifies the story in attributing... Читать дальше...

Quantifying fair income distribution in Thailand

Plos.org 

by Thitithep Sitthiyot, Kanyarat Holasut

Given a vast concern about high income inequality in Thailand as opposed to empirical findings around the world showing people’s preference for fair income inequality over unfair income equality, it is therefore important to examine whether inequality in income distribution in Thailand over the past three decades is fair, and what fair inequality in income distribution in Thailand should be. To quantitatively measure fair income distribution, this... Читать дальше...

Association between rosacea and helicobacter pylori infection: A meta-analysis

Plos.org 

by Ying Gao, Xiao-jing Yang, Yun Zhu, Ming Yang, Fei Gu

Background and objectives

The potential association between rosacea and a heightened prevalence of Helicobacter pylori (HP) infection has been previously suggested. However, existing studies offer inconsistent results. This systematic review and meta-analysis aimed to elucidate the relationship between rosacea and HP infection.

Methods

We conducted comprehensive searches of PubMed, Embase, and Web of Science databases to identify... Читать дальше...



What determines participation in sport for older adults in England: A multilevel analysis of Active Lives data

Plos.org 

by Andrew Brinkley, Gavin Sandercock, Ruth Lowry, Paul Freeman

Physical inactivity within an ageing population is an ongoing public health concern for policymakers. Engagement in sport forms a foundation of policy designed to encourage physical activity participation and improve health and wellbeing. This study aimed to (i) understand the extent to which older adults participate in sport and the (ii) correlates that predict this involvement within an English population sample of older adults. Читать дальше...

Knowledge-attitude and practice of Anthrax and brucellosis: Implications for zoonotic disease surveillance and control in pastoral communities of Afar and Somali region, Ethiopia

Plos.org 

by Rea Tschopp, Ashenafi GebreGiorgis Kidanu

Background

Anthrax and brucellosis are endemic national priority zoonotic diseases in Ethiopia. This study assess the possible factors explaining the current limited information available on animal and human cases in pastoral communities.

Methods

Two questionnaire surveys gathered data from 509 pastoralists and 51 healthcare providers between February and April 2019 in five districts of Afar and the Somali region (SRS).

Results

Among the 51 healthcare providers... Читать дальше...

Modelling cell shape in 3D structured environments: A quantitative comparison with experiments

Plos.org 

by Rabea Link, Mona Jaggy, Martin Bastmeyer, Ulrich S. Schwarz

Cell shape plays a fundamental role in many biological processes, including adhesion, migration, division and development, but it is not clear which shape model best predicts three-dimensional cell shape in structured environments. Here, we compare different modelling approaches with experimental data. The shapes of single mesenchymal cells cultured in custom-made 3D scaffolds were compared by a Fourier method with surfaces that... Читать дальше...

Chaperone Hsp70 helps Salmonella survive infection-relevant stress by reducing protein synthesis

Plos.org 

by Carissa Chan, Eduardo A. Groisman

In all domains of life, Hsp70 chaperones preserve protein homeostasis by promoting protein folding and degradation and preventing protein aggregation. We now report that the Hsp70 from the bacterial pathogen Salmonella enterica serovar Typhimurium—termed DnaK—independently reduces protein synthesis in vitro and in S. Typhimurium facing cytoplasmic Mg2+ starvation, a condition encountered during infection. This reduction reflects a 3-fold increase in ribosome... Читать дальше...

Mutualism on the edge: Understanding the Paramecium–Chlorella symbiosis

Plos.org 

by Benjamin H. Jenkins

Exploring the mechanisms that underpin symbiosis requires an understanding of how these complex interactions are maintained in diverse model systems. The ciliate protist, Paramecium bursaria, offers a valuable insight into how emergent endosymbiotic interactions have evolved. Exploring the mechanisms that underpin symbiosis requires an understanding of how these complex interactions are maintained in diverse model systems. This Perspective discusses how the ciliate... Читать дальше...





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