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2018

Новости за 02.10.2018

Diagnostic value of STAF score in combination with D-dimer in cardioembolism

Plos.org 

by Li-Bin Liu, Ya-Dong Guo, An-Ding Xu, Jie-Xi Zhong, Wen-Yan Zhuo

The aim of this study was to evaluate the diagnostic value of the Score for the Targeting of Atrial Fibrillation (STAF) in combination with the serum D-dimer (DD) levels in cardioembolism(CE).This study was a retrospective case-onlystudy, consecutively including patients with acute ischemic stroke. All patients were evaluated following the STAF scoring criteria and were classified according to the Trial of ORG 10172 in Acute... Читать дальше...

Isolated perfused working hearts provide valuable additional information during phenotypic assessment of the diabetic mouse heart

Plos.org 

by Tina M. Pedersen, Neoma T. Boardman, Anne D. Hafstad, Ellen Aasum

Although murine models for studying the development of cardiac dysfunction in diabetes mellitus are well established, their reported cardiac phenotypes vary. These reported divergences may, in addition to the severity of different models, also be linked to the methods used for cardiac functional assessment. In the present study, we examined the functional changes using conventional transthoracic echocardiography (in vivo)... Читать дальше...



Transcriptome analyses of Atlantic salmon muscle genes induced by a DNA vaccine against salmonid alphavirus, the causative agent of salmon pancreas disease (PD)

Plos.org 

by Mehrdad Sobhkhez, Aleksei Krasnov, Børre Robertsen

Salmonid alphavirus (SAV) is the causative agent of pancreas disease (PD) in farmed Atlantic salmon. A previous study showed that vaccination of pre-smolt salmon with a plasmid encoding the structural polypeptide of SAV gave protection against infection and development of PD accompanied by production of antibodies against the virus. In the present work we analyzed transcript responses in the muscle to vaccination with this plasmid (here named pSAV). Читать дальше...

Workload implications for clinic workflow with implementation of three-dimensional printed customized bolus for radiation therapy: A pilot study

Plos.org 

by Eric Ehler, David Sterling, Kathryn Dusenbery, Jessica Lawrence

Bolus is commonly used in radiation therapy to improve radiation dose distribution to the target volume, but commercially available products do not always conform well to the patient surface. Tumor control may be compromised, particularly for superficial tumors, if bolus does not conform well and air gaps exist between the patient surface and the bolus. Three-dimensional (3D) printing technology allows the creation of highly detailed... Читать дальше...

Blaunet: An R-based graphical user interface package to analyze Blau space

Plos.org 

by Michael Genkin, Cheng Wang, George Berry, Matthew E. Brashears

McPherson’s Blau space and affiliation ecology model is a powerful tool for analyzing the ecological competition among social entities, such as organizations, along a combination of sociodemographic characteristics of their members. In this paper we introduce the R-based Graphical User Interface (GUI) package Blaunet, an integrated set of tools to calculate, visualize, and analyze the statuses of individuals and social entities in Blau space... Читать дальше...

Impact of maternal western diet-induced obesity on offspring mortality and peripheral endocannabinoid system in mice

Plos.org 

by Pedro A. Perez, Nicholas V. DiPatrizio

Over two-thirds of adults in the United States are obese or overweight, which is largely due to chronic overconsumption of diets high in fats and sugars (i.e., Western diet). Recent studies reveal that maternal obesity may predispose offspring to development of obesity and other metabolic diseases; however, the molecular underpinnings of these outcomes are largely unknown. The endocannabinoid system is an important signaling pathway that controls feeding behavior and energy homeostasis... Читать дальше...





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