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Новости за 25.01.2023

Astronomers discover a peculiar cataclysmic variable star

Phys.org 

Using NASA's Transiting Exoplanet Survey Satellite (TESS), astronomers have discovered a peculiar cataclysmic variable star. The newly found system, designated SDSS J134441.83+204408.3 (or J1344 for short) is a highly asynchronous, short-period magnetic cataclysmic variable, despite its high surface field strength. The finding is reported in a paper published January 13 on the arXiv preprint server.

Duke Fans Are Spoiled

Duke Basketball Report 

Jan 11, 2023; Durham, North Carolina, USA; Duke Blue Devils head coach Jon Scheyer directs his team during the second half against the Pittsburgh Panthers at Cameron Indoor Stadium.  | Rob Kinnan-USA TODAY Sports

And they need to get over it.

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MMO 2023 Top 30 Mets Prospects: 25-21 Led By William Lugo

Mets Merized Online 

This is the second edition of the 2023 MMO prospect countdown with the previous post featuring entirely right-handed pitchers. 25. Jacob Reimer, 3B B/T: R/R     Age: 2/22/2004 (18) Ht: 6’2″        Wt: 205 lb. Acquired: 2022 Fourth Round Pick from Yucaipa HS (Yucaipa, CA) ETA: 2027    Previous Ranks: N/A 2022 Stats (FCL): .261/.414/.478, 3B, HR, […]

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House AR / Fernandes Atem Arquitetos

Archdaily.com 

Built on a conventional plot of a gated community in the city of Eusebio, Metropolitan Region of Fortaleza, Casa AR was conceived with the intention of maximizing the integrative character of its interior spaces. The orientation of the land, whose front faces west, was decisive for the architectural design. 



TYMV and TRV infect Arabidopsis thaliana by expressing weak suppressors of RNA silencing and inducing host RNASE THREE LIKE1

Plos.org 

by Hayat Sehki, Agnès Yu, Taline Elmayan, Hervé Vaucheret

Post-Transcriptional Gene Silencing (PTGS) is a defense mechanism that targets invading nucleic acids of endogenous (transposons) or exogenous (pathogens, transgenes) origins. During plant infection by viruses, virus-derived primary siRNAs target viral RNAs, resulting in both destruction of single-stranded viral RNAs (execution step) and production of secondary siRNAs (amplification step), which maximizes the plant defense. As a counter-defense... Читать дальше...

The educational effects of emergency remote teaching practices—The case of covid-19 school closure in Italy

Plos.org 

by Alice Bertoletti, Mara Soncin, Marta Cannistrà, Tommaso Agasisti

The disruption caused by the Covid-19 pandemic generated an unprecedented situation, in which digital learning, in the form of Emergency Remote Teaching, was the only possible form of schooling. Italy soon decided to close schools as a measure to counter the spread of the virus. Although the Ministry of Education suggested general guidelines, school principals and teachers were autonomous in deciding how to best organise their educational activities. Читать дальше...

Improved slime mould algorithm based on hybrid strategy optimization of Cauchy mutation and simulated annealing

Plos.org 

by Xiaoyi Zhang, Qixuan Liu, Xinyao Bai

In this article, an improved slime mould algorithm (SMA-CSA) is proposed for solving global optimization and the capacitated vehicle routing problem (CVRP). This improvement is based on the mixed-strategy optimization of Cauchy mutation and simulated annealing to alleviate the lack of global optimization capability of the SMA. By introducing the Cauchy mutation strategy, the optimal solution is perturbed to increase the probability of escaping from the local extreme value; in addition... Читать дальше...

Impact of valproic acid on busulfan pharmacokinetics: In vitro assessment of potential drug-drug interaction

Plos.org 

by Bashayer F. Al-Enezi, Nada Al-Hasawi, Kamal M. Matar

Busulfan (Bu) is an alkylating agent commonly used at high doses in the preparative regimens of hematopoietic stem cell transplantation (HSCT). It has been shown that such high doses of Bu are associated with generalized seizures which are usually managed by prophylactic antiepileptic drugs (AEDs) such as valproic acid (VPA). Being a strong enzyme inhibitor, VPA may inhibit Bu metabolism and thus increase its potential toxicity. Despite its clinical relevance... Читать дальше...

The size of larval rearing container modulates the effects of diet amount and larval density on larval development in Aedes aegypti

Plos.org 

by Alima Qureshi, Elizabeth Keen, George Brown, Lauren Cator

Mass-rearing of mosquitoes under laboratory conditions is an important part of several new control techniques that rely on the release of males to control mosquito populations. While previous work has investigated the effect of larval density and diet amount on colony productivity, the role of the size of the container in which larval development takes place has been relatively ignored. We investigated the role of container size... Читать дальше...

Maternal and neonatal outcomes of singleton versus twin pregnancies complicated by gestational diabetes mellitus: A systematic review and meta-analysis

Plos.org 

by Fengming Tu, Aimei Fei

Background

There is limited evidence exploring the maternal and neonatal complications of gestational diabetes mellitus (GDM) following singleton or twin pregnancies. Further, there have been no reviews completed examining the possible risk factors associated with GDM in singleton compared to twin pregnancies. This study assesses the impact of GDM in singleton and twin pregnancies on maternal and neonatal outcomes.

Methods

From 1954 to December 2021, a thorough... Читать дальше...

SARS-CoV-2 variants-associated outbreaks of COVID-19 in a tertiary institution, North-Central Nigeria: Implications for epidemic control

Plos.org 

by Oluwapelumi Olufemi Adeyemi, Nnaemeka Darlington Ndodo, Mariam Kehinde Sulaiman, Oyeronke Temidayo Ayansola, Oluwabunmi Idera Nimat Buhari, Olusola Anuoluwapo Akanbi, Oladimeji Akeem Bolarinwa, Chimaobi Chukwu, Ireoluwa Yinka Joel, Adesuyi Ayodeji Omoare, Kolawole Wasiu Wahab, Celestina Obiekea, Mikhail Olayinka Buhari, Anthony Ahumibe, Caroline Folasade Kolawole, Catherine Okoi, Olumuyiwa Babagbemi Omotesho, Nwando Mba, Oluwafemi Adeniyi, Olajumoke Babatunde, Nathaniel Akintunde, Ganiu Ayinla... Читать дальше...

The Q163C/Q309C mutant of αMI-domain is an active variant suitable for NMR characterization

Plos.org 

by Hoa Nguyen, Tianwei Jing, Xu Wang

Integrin αMβ2 (Mac-1, CD11b/CD18, CR3) is an important adhesion receptor expressed on monocytes. Mac-1 is responsible for mediating cell migration, phagocytosis, degranulation as well as cell-cell fusion. It is also the most promiscuous integrin in terms of ligand specificity with over 100 ligands, most of which use the αMI-domain as their binding site. Despite the importance of αMI-domain in defining ligand interactions of Mac-1, structural studies of... Читать дальше...





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