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2023

Новости за 09.03.2023

The impact of Covid-19 pandemic on overall well-being of practicing lawyers

Plos.org 

by Michael Fore, Erin Stevenson

Every day lawyers provide counsel and advocacy to individuals, groups, and businesses in a multitude of settings. From court room to board room, attorneys are relied upon to guide their clients through difficult situations. In doing this, attorneys all too often internalize the stresses of those that they help. The legal system has long been considered a stressful occupation. This stressful environment was further taxed by the wider societal disruptions in... Читать дальше...

Effects of preharvest sprays of iodine, selenium and calcium on apple biofortification and their quality and storability

Plos.org 

by Paweł Wójcik

The low dietary intake of iodine (I) and selenium (Se) by humans leads to serious health and socioeconomic problems. Therefore, enrichment of plants with I and Se using fertilisers containing these micronutrients is commonly recommended. In this study, we examined the impacts of combined spraying of I as iodide or iodate, Se as selenite or selenate, and calcium (Ca) as Ca-chloride on the enrichment of ‘Red Jonaprince’ (Malus domestica Borth.) apples, as well as fruit quality and their storability. Читать дальше...



Testicular histone hyperacetylation in mice by valproic acid administration affects the next generation by changes in sperm DNA methylation

Plos.org 

by Kazuya Sakai, Kenshiro Hara, Kentaro Tanemura

Various studies have described epigenetic inheritance through sperms. However, the detailed mechanisms remain unclear. In this study, we focused on DNA methylation in mice treated with valproic acid (VPA), an inducer of epigenomic changes, and analyzed the treatment effects on the sperm from the next generation of mice. The administration of 200 mg/kg/day VPA to mice for 4 weeks caused transient histone hyperacetylation in the testes and DNA methylation changes in the sperm... Читать дальше...

3D-printed eye model: Simulation of intraocular pressure

Plos.org 

by Hidenaga Kobashi, Masaaki Kobayashi

Purpose

To develop artificial eye models using 3D printing and to evaluate the correlation between different corneal thicknesses and intraocular pressures (IOPs).

Methods

We designed 7 artificial eye models using a computer-aided design system and fabricated them using 3D printing. Corneal curvature and axial length were based on the Gullstrand eye model. Hydrogels were injected into the vitreous cavity, and seven different corneal thicknesses (200 to 800 μm) were prepared. Читать дальше...

Detection of genes with differential expression dispersion unravels the role of autophagy in cancer progression

Plos.org 

by Christophe Le Priol, Chloé-Agathe Azencott, Xavier Gidrol

The majority of gene expression studies focus on the search for genes whose mean expression is different between two or more populations of samples in the so-called “differential expression analysis” approach. However, a difference in variance in gene expression may also be biologically and physiologically relevant. In the classical statistical model used to analyze RNA-sequencing (RNA-seq) data, the dispersion, which defines the variance... Читать дальше...

Orion notes continuing progress at Northern Cape projects

Miningweekly.com 

Exploration and development company Orion Minerals continued to progress its strategy of building a high-quality pipeline of future facing base metals development and exploration assets to supply the demands created by a global clean energy transition, the company notes in its interim financial report for the six months ended December 31. Orion noted strong progress with financing and predevelopment activities at the development ready Prieska copper/zinc project, as well as progressing exploration... Читать дальше...

Minister: Abolishing free public transport not a magic solution

Err.ee (en) 

Estonian Minister of the Environment Madis Kallas (SDE), whose party is currently involved in coalition talks over the formation of a new government, does not believe that abolishing free public transport is the way to make the savings required to balance the state budget.

La Niña is officially over, NOAA announces: What does that mean? - The Hill

Top Stories (us) - Google News (com) 

  1. La Niña is officially over, NOAA announces: What does that mean?  The Hill
  2. Forecasters: La Nina, weather's unwanted nasty guest, leaves  The Associated Press - en Español
  3. La Nina is over, National Weather Service declares  The Washington Post
  4. La Niña Has Ended, and El Niño May Be on the Way  The New York Times
  5. After 3 brutal years, La Nina weather phenomenon is gone for now  KOMO News
  6. View Full Coverage on Google News





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