A new treasure trove for obsessive fans of 'The Shining' (you know who you are)
'Coco' director Lee Unkrich is a 'Shining' aficionado. He walks us through his new box set of revelations and ephemera on Stanley Kubrick's 'The Shining.'
'Coco' director Lee Unkrich is a 'Shining' aficionado. He walks us through his new box set of revelations and ephemera on Stanley Kubrick's 'The Shining.'
The Los Angeles Lakers are favored to prevail over the visiting Dallas Mavericks on Friday, March 17.
The redesigned Toontown is entirely wheelchair accessible and is visually and auditorily approachable for kids who are easily overwhelmed.
By Lauren Vinopal Published: March 17th, 2023
Initially known as Casa MIC, Curitiba's iconic brutalist residence, it is an original project of renowned architect Manoel Coelho, built in 1981, where he and his family lived for 40 years.
by Maikell Segovia, Philipp Schwabl, Salem Sueto, Candy Cherine Nakad, Juan Carlos Londoño, Marlenes Rodriguez, Manuel Paiva, Martin Stephen Llewellyn, Hernán José Carrasco
Читать дальше...
by Reyhaneh Tirgar, Jonathan P. Davies, Lars Plate, Jared T. Nordman
Histones are essential for chromatin packaging, and histone supply must be tightly regulated as excess histones are toxic. To drive the rapid cell cycles of the early embryo, however, excess histones are maternally deposited. Therefore, soluble histones must be buffered by histone chaperones, but the chaperone necessary to stabilize soluble H3-H4 pools in the Drosophila embryo has yet to be identified. Here, we show that CG8223... Читать дальше...
by Liangjie Sun, Yushan Qiu, Wai-Ki Ching, Pu Zhao, Quan Zou
During breast cancer metastasis, the developmental process epithelial-mesenchymal (EM) transition is abnormally activated. Transcriptional regulatory networks controlling EM transition are well-studied; however, alternative RNA splicing also plays a critical regulatory role during this process. Alternative splicing was proved to control the EM transition process, and RNA-binding proteins were determined to regulate alternative splicing. Читать дальше...
by Hui Peng, Limsoon Wong, Wilson Wen Bin Goh
In mass spectrometry (MS)-based proteomics, protein inference from identified peptides (protein fragments) is a critical step. We present ProInfer (Protein Inference), a novel protein assembly method that takes advantage of information in biological networks. ProInfer assists recovery of proteins supported only by ambiguous peptides (a peptide which maps to more than one candidate protein) and enhances the statistical confidence for proteins supported by both unique and ambiguous peptides. Читать дальше...
by Alasdair D. F. Clarke, Amelia R. Hunt, Anna E. Hughes
by Tian-Yeh Lim, Blake R. Wilde, Mallory L. Thomas, Kristin E. Murphy, Jeffery M. Vahrenkamp, Megan E. Conway, Katherine E. Varley, Jason Gertz, Donald E. Ayer
Читать дальше...
by Yuka Koike, Sarah Pickles, Virginia Estades Ayuso, Karen Jansen-West, Yue A. Qi, Ziyi Li, Lillian M. Daughrity, Mei Yue, Yong-Jie Zhang, Casey N. Cook, Dennis W. Dickson, Michael Ward, Leonard Petrucelli, Mercedes Prudencio
Читать дальше...
The ChatGPT API can help address some of the web interface's shortcomings. Here's how to maximize the API for specific SEO use cases.
Читать дальше...The team behind NASA’s James Webb Space Telescope received the 2023 Robert H. Goddard Memorial Trophy at the National Space Club’s yearly Dr. Robert H. Goddard Memorial Dinner in Washington on March 10.
Photo by Kevork Djansezian/Getty Images
Rounding up all the Warriors and NBA news from around the web.
Читать дальше...Photo by Al Bello/Getty Images
It’s a tough time to be a pitcher.
Читать дальше...Darren Yamashita-USA TODAY Sports
MLB news roundup
Happy Friday, Athletics Nation!
Don’t drop that ball, Cristian Pache!
That isn’t so much a worry for the young outfielder, who is renowned for his elite defensive skills. The real worry is that his hitting was terrible last year: In 260 plate appearances, Pache slashed .166/.218/.241 with a wRC+ of 35 for the A’s in 2022. To top it off, the 24-year-old centerpiece of the Matt Olson trade is one of four Athletics who... Читать дальше...
Nate Eaton #18 of the Kansas City Royals gives high-fives to teammates after scoring in the top of the first against the Milwaukee Brewers at American Family Fields of Phoenix on March 11, 2023 in Phoenix, Arizona. | Photo by Patrick Mulligan/Getty Images
An intriguing player
Читать дальше...Photo by David Berding/Getty Images
Will Trevor Stephan be worth more or less than 0.4 fWAR in 2023?
Читать дальше...
UHV will look to maintain its recent form when it travels to Louisiana to face No. 4-ranked LSU-Shreveport.
Tim Bradley (center) gives his in depth analysis of the upcoming super middleweight showdown. | Photo by Mikey Williams/Top Rank Inc via Getty Images
Timothy Bradley wants to give the edge to Caleb Plant over David Benavidez, but questions his ability to keep it all together going down the stretch of the fight.
Читать дальше...
The long wait is over.
It's been a month since we checked in with our friends at the Gaffney Medical Center, but the series is back on March 22.
Chicago Med Season 8 Episode 16 will make up for the long hiatus by getting viewers' adrenaline pumping during a high-stakes rescue story. And CFD will assist in a semi-crossover between Med and Chicago Fire.
Before COVID, characters traveled between One Chicago shows regularly. Med's original premise was a semi-crossover... Читать дальше...
by Yi-Sheng Kao, Li-Chiu Wang, Po-Chun Chang, Heng-Ming Lin, Yee-Shin Lin, Chia-Yi Yu, Chien-Chin Chen, Chiou-Feng Lin, Trai-Ming Yeh, Shu-Wen Wan, Jen-Ren Wang, Tzong-Shiann Ho, Chien-Chou Chu, Bo-Cheng Zhang, Chih-Peng Chang
Читать дальше...
by Yuan Gao, Xiaocheng Zhang, Tingting Jiang, Hao Zhou, Hua Liu, Yuan Hu, Jianping Cao
Читать дальше...
by Yolandie Kriel, Cecilia Milford, Joanna Paula Cordero, Fatima Suleman, Petrus S. Steyn, Jennifer Ann Smit
Читать дальше...