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Новости за 23.03.2023

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Combining viral genomics and clinical data to assess risk factors for severe COVID-19 (mortality, ICU admission, or intubation) amongst hospital patients in a large acute UK NHS hospital Trust

Plos.org 
En

by Max Foxley-Marrable, Leon D’Cruz, Paul Meredith, Sharon Glaysher, Angela H. Beckett, Salman Goudarzi, Christopher Fearn, Kate F. Cook, Katie F. Loveson, Hannah Dent, Hannah Paul, Scott Elliott, Sarah Wyllie, Allyson Lloyd, Kelly Bicknell, Sally Lumley, James McNicholas, David Prytherch, The COVID-19 Genomics UK (COG-UK) consortium , Andrew Lundgren, Or Graur, Anoop J. Chauhan, Samuel C. Robson

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Potential molecular and cellular mechanisms for adverse placental outcomes in pregnancies complicated by SARS-CoV-2 infection—A scoping review

Plos.org 
En

by Janelle Y. Wai, Eilidh M. Wood, Kylie K. Hornaday, Donna M. Slater

Background

Emerging evidence suggests that SARS-CoV-2 infection during pregnancy can result in placental damage and poor placental outcomes. However, the mechanisms by which SARS-CoV-2 infection leads to placental damage are not well understood. With a rapid expansion of literature on this topic, it is critical to assess the quality and synthesize the current state of literature. The objective of this scoping review is... Читать дальше...

Авторские публикации Smi24.net

Comparison of alcohol consumption and tobacco use among Korean adolescents before and during the COVID-19 pandemic

Plos.org 
En

by Wonseok Jeong

Background

The COVID-19 pandemic has brought significant changes worldwide, and due to the strict “Social Distancing Plan” including school closures, Korean adolescents have experienced unprecedented changes in their lives. Considering the peer effect on adolescents’ health behavior impacted due to the changes brought about by the pandemic, it would be interesting to explore differences in substance use in Korean adolescents. This study examines how these risk behaviors... Читать дальше...



A comprehensive study of Ecuadorian adult patients with a mild and moderate presentation of COViD-19

Plos.org 
En

by Fabricio González-Andrade, Yenddy Carrero

Aim

To characterize non-hospitalized patients with mild and moderate clinical presentation.

Methods

We performed an epidemiological, observational, descriptive, and cross-sectional study carried out in Ecuador, with 1,447 participants between 18 and 66 years, non-hospitalized, with a molecular RT-PCR test for SARS-CoV2. We analyzed demographic characteristics according to sex, age group, clinical findings, behavior after diagnosis, family and social behavior... Читать дальше...

Effect of inferior oblique myectomy on ocular torsion according to the absence of the trochlear nerve in unilateral congenital superior oblique palsy

Plos.org 
En

by Yeji Moon, Byung Joo Lee

Objectives

To evaluate the effect of inferior oblique (IO) myectomy on ocular torsion according to the absence of the trochlear nerve in unilateral congenital superior oblique palsy (UCSOP).

Methods

We retrospectively reviewed the clinical data of patients who had been diagnosed with UCSOP and underwent ipsilateral IO myectomy (n = 43). Patients were classified into the present and absent groups according to the absence of the trochlear nerve and superior... Читать дальше...

Impact of early nutrition and feeding route on clinical outcomes of neurocritically ill patients

Plos.org 
En

by Young Kyun Choi, Hyun-Jung Kim, Joonghyun Ahn, Jeong-Am Ryu

Early proper nutritional support is important to critically ill patients. Nutritional support is also associated with clinical outcomes of neurocritically ill patients. We investigate whether early nutrition is associated with clinical outcomes in neurocritically ill patients. This was a retrospective, single-center, observational study including neurosurgical patients who were admitted to the intensive care unit (ICU) from January 2013 to December 2019. Читать дальше...

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Суд оштрафовал Смолова за неуплату прошлогоднего штрафа Сотрудники Свердловского филиала приняли участие в международной промышленной выставке «ИННОПРОМ» в Екатеринбурге Менеджер Артиста. Менеджер по работе с артистами. Актер Сердюк понадеялся, что ремейк "Моей прекрасной няни" получится не хуже оригинала

Chronic Salmonella Typhi carriage at sites other than the gallbladder

Plos.org 
En

by Seth A. Hoffman, Michael J. Sikorski, Myron M. Levine

Typhoid fever caused by infection with Salmonella enterica subspecies enterica serotype Typhi (S. Typhi), an important public health problem in many low- and middle-income countries, is transmitted by ingestion of water or food contaminated by feces or urine from individuals with acute or chronic S. Typhi infection. Most chronic S. Typhi carriers (shedding for ≥12 months) harbor infection in their gallbladder wherein preexisting pathologies... Читать дальше...

Modulating the Kynurenine pathway or sequestering toxic 3-hydroxykynurenine protects the retina from light-induced damage in Drosophila

Plos.org 
En

by Sarita Hebbar, Sofia Traikov, Catrin Hälsig, Elisabeth Knust

Tissue health is regulated by a myriad of exogenous or endogenous factors. Here we investigated the role of the conserved Kynurenine pathway (KP) in maintaining retinal homeostasis in the context of light stress in Drosophila melanogaster. cinnabar, cardinal and scarlet are fly genes that encode different steps in the KP. Along with white, these genes are known regulators of brown pigment (ommochrome) biosynthesis. Using white as a sensitized genetic background... Читать дальше...

A systematic evaluation of deep learning methods for the prediction of drug synergy in cancer

Plos.org 
En

by Delora Baptista, Pedro G. Ferreira, Miguel Rocha

One of the main obstacles to the successful treatment of cancer is the phenomenon of drug resistance. A common strategy to overcome resistance is the use of combination therapies. However, the space of possibilities is huge and efficient search strategies are required. Machine Learning (ML) can be a useful tool for the discovery of novel, clinically relevant anti-cancer drug combinations. In particular, deep learning (DL) has become a popular... Читать дальше...

Спонсорский контент
Russia24.pro
Аймед — лидер в микрохирургии: премия «I’M FAMOUS» отметила достижения Нужно ли праздновать патриотические праздники в колониях-поселениях? Глобальное масштабирование: компания «Газинформсервис» участвует в обсуждении применения электронной транспортной накладной с ЕЭК ООН Искусство как память: в Театре Российской Армии прошел уникальный балетный марафон
Ria.city
Искусство как память: в Театре Российской Армии прошел уникальный балетный марафон Нужно ли праздновать патриотические праздники в колониях-поселениях? Киберпреступность эволюционировала, защита не может строиться только на поиске вредоносного кода Глобальное масштабирование: компания «Газинформсервис» участвует в обсуждении применения электронной транспортной накладной с ЕЭК ООН


Ru24.net
Собянин: 250 млрд рублей вложат в развитие рабочих мест у метро Москвы Ждем вас в эфире в 16.30!. Глава татарской национально-культурной автономии Москвы, один из инициаторов самого крупного в мире Сабантуя, пошедшего в российской столице, Фарит Фарисов в авторской программе писателя и... Аймед — лидер в микрохирургии: премия «I’M FAMOUS» отметила достижения Примаков призвал определиться с отношением к странам СНГ

Все города России
Smi24.net
Организаторы премии "Шум" проведут молодежный блог-тур по ярким местам России Потолок обрушился в московском ТРЦ «Ривьера», есть пострадавший В СК возбудили уголовное дело после ДТП с участием автобуса в Ступино 3D-формы для сложных отливок: новое производство откроется в Москве к 2026 году

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