We live in a divided world, but one thing most people can agree on right now is that the cost of housing is way too high. Home prices have slipped a bit, but home prices, mortgage rates, and rents remain sky-high in a lot of places, and a lot of people—especially younger folks—are despairing of ever owning a home.…
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Daniil Medvedev addressed the challenge of facing Carlos Alcaraz ahead of the Madrid Open, where the pair are the top two seeds.
Kirby Lee-USA TODAY Sports
Which teams will spin the wheel on these high-ceiling, low-floor prospects?
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Is Chef Richard Blais the kitchen whisperer?
His skills have successfully gotten many Next Level Chefs out of the basement and on their way to the top again.
This Thursday, Chef Blaise might have his work cut out for him.
Chefs often have specialties.
Not every great chef can both whip together a perfect meal and top if off with a delicious dessert.
The Next Level Chefs will be put to the test when they're asked to forgo the meal and get dessert on the table. Читать дальше...
Photo by Scott Kane/Getty Images
Things might not be great for the Mariners, but the Cardinals are really down bad.
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Gary A. Vasquez-USA TODAY Sports
MLB news roundup
Happy Thursday, AN!
Last night’s game had its positives to go with the low points. Luis Medina made his MLB debut and struck out arguably the best player in baseball twice, but also got hit hard and gave up a ton of runs.
Among the positives is the fact that Medina made it through five full innings, something he had yet to do in Triple-A this year. The right-handed rookie had his longest start of the year and threw 93 pitches in his big league debut. Читать дальше...
In the middle of March, the SoxProspects.com Brass made our annual trip to Spring Training to catch the action on the back fields in minor league camp. I was able to spend a full week in Fort Myers this year, and as a result I was able to see more players than ever before. Today I’ll focus on some deeper names to watch out for this year.
Читать дальше...Amazon Studios
There’s a lot riding on Citadel, Amazon’s wannabe-franchise series, what with its reported $200 million-plus price tag (making it the second most expensive TV venture ever, after The Lord of the Rings: The Rings of Power), designs for multiple international spin-offs, and a second-season renewal ahead of its April 28 Prime Video premiere. The streamer and executive-producers Joe and Anthony Russo have bet the house on their long-gestating spy saga, which was announced in 2018 and... Читать дальше...
In response to the IEA’s warning made on Wednesday that OPEC should be careful not to cut too much production lest they jack up prices too high, the Organization of the Petroleum Exporting Countries (OPEC) issued a warning of its own to the IEA: your calls to stop investing in oil and gas is what could lead to future price volatility, OPEC said in a Thursday statement. The IEA’s warning was simple: OPEC should be careful not to cut production too much, lest crude oil prices rise to the point where... Читать дальше...
by Elisa Casadei, Irene Salinas
by Jereme G. Spiers, Hsiao-Jou Cortina Chen, Joern R. Steinert
Prion diseases, also known as transmissible spongiform encephalopathies, are rare, progressive, and fatal neurodegenerative disorders, which are caused by the accumulation of the misfolded cellular prion protein (PrPC). The resulting cytotoxic prion species, referred to as the scrapie prion isoform (PrPSc), assemble in aggregates and interfere with neuronal pathways, ultimately rendering neurons dysfunctional. As the prion protein... Читать дальше...
by Yukiko Yano, Emily Vogtmann, Alaina H. Shreves, Stephanie J. Weinstein, Amanda Black, Norma Diaz-Mayoral, Yunhu Wan, Weiyin Zhou, Xing Hua, Casey L. Dagnall, Amy Hutchinson, Kristine Jones, Belynda D. Hicks, Kathleen Wyatt, Michelle Brotzman, Nicole Gerlanc, Wen-Yi Huang, Paul S. Albert, Nicolas Wentzensen, Christian C. Abnet
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by Ashrenee Govender, Sean T. Fennessy, Sean N. Porter, Johan C. Groeneveld
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by Weibo Zheng, Hong Zhou
This paper considers the problem that a depot replenishes several shelters by aerial and land transportation modes for disaster relief. There are two distinguishing features of our problem: one is routing decisions determine replenishment lead times; the other is that we introduce dual sourcing policy into the inventory routing problem. A robust optimization model is proposed to determine the optimal replenishment quantity, replenishment mode, and transportation routes. Читать дальше...
by Nurul Azmawati Mohamed, Hana Maizuliana Solehan, Mohd Dzulkhairi Mohd Rani, Muslimah Ithnin, Mahalecthumy Arujanan
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by Edmund Ndudi Ossai, Irene Ifeyinwa Eze, Chukwuma David Umeokonkwo, Chukwuemeka Obioma Izuagba, Lawrence Ulu Ogbonnaya
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by Louis J. Gross, Rachel Patton McCord, Sondra LoRe, Vitaly V. Ganusov, Tian Hong, W. Christopher Strickland, David Talmy, Albrecht G. von Arnim, Greg Wiggins
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by Matthias F. C. Hudecek, Simon Lemster, Peter Fischer, Julia Cecil, Dieter Frey, Susanne Gaube, Eva Lermer
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by Shengfeng Xie, Caimin Jin, Ting Song, Chengxiao Feng
Digital finance provides a long-tail mechanism for alleviating relative poverty caused by unequal opportunities and rights. According to the inference of an improved Cobb-Douglas production function and Ramsey-Cass-Koopmans two-stage household consumption model, the long-tail mechanism for digital finance to alleviate the relative poverty of farmers includes productive investment mechanism, credit mechanism, financial asset allocation and entrepreneurial mechanism. Читать дальше...
by Rakan K. Alhabib, Noara Alhusseini, Anas G. Aboalsamh, Ghaith Adi, Aya Ismail, Amro Hajja, Duaa Alammari, Ziad Khalil, Maha A. Alharbi, Sarah K. Albahiti
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by Mirza Ahmar Beg, Abdur Rehman, Lubna Rehman, Rizwan Ullah, Faiza Farhat, Sobia Wasim, S. M. A. Abidi
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by Münteha Girgin, Sevim Isik, Nigar Kantarci-Carsibasi
Alzheimer’s disease (AD) is a neurodegenerative disorder considered as a global public health threat influencing many people. Despite the concerning rise in the affected population, there is still a shortage of potent and safe therapeutic agents. The aim of this research is to discover novel natural source molecules with high therapeutic effects, stability and less toxicity for the treatment of AD, specifically targeting acetylcholinesterase (AChE). Читать дальше...
by Dennis Aizobu, Yusuf H. Wada, Jennifer Anyanti, Godpower Omoregie, Boluwatife Adesina, Serah Malaba, Morghan Kabeer, Samuel Oyegunle, Akudo Ikpeazu, Omokhudu Idogho
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by Edita Ritmejerytė, Berin A. Boughton, Michael J. Bayly, Rebecca E. Miller
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by Cathinka Thyness, Hilde Grimstad, Aslak Steinsbekk
ObjectiveTo investigate the association between European medical students’ psychological safety in and experiences from their last supervised patient encounter.
Materials and methodsA cross-sectional online survey among European medical students. Bivariable and multivariable linear regression was used to explore the associations between the dependent variable psychological safety and independent variables concerning students’... Читать дальше...