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Новости за 04.05.2023

Characterization of a pathway of genomic instability induced by R-loops and its regulation by topoisomerases in E. coli

Plos.org 

by Julien Brochu, Émilie Vlachos-Breton, Dina Irsenco, Marc Drolet

The prototype enzymes of the ubiquitous type IA topoisomerases (topos) family are Escherichia coli topo I (topA) and topo III (topB). Topo I shows preference for relaxation of negative supercoiling and topo III for decatenation. However, as they could act as backups for each other or even share functions, strains lacking both enzymes must be used to reveal the roles of type IA enzymes in genome maintenance. Recently, marker... Читать дальше...

Reimagining the future of natural history museums with compassionate collection

Plos.org 

by Allison Q. Byrne

Compassionate collection involves minimizing harm while collecting museum data in the field. By adopting this practice, natural history museums could better maintain existing collections, accommodate more nonlethal specimens and data, and foster an inclusive community. This Perspective advocates for the adoption of compassionate collection practices, through which natural history museums can better maintain existing collections, accommodate more non-lethal specimens and data... Читать дальше...

An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis

Plos.org 

by Chengliang Wang, Jianbin Ruan

The gasdermins are a family of pore-forming proteins involved in various cellular processes such as cell death and inflammation. A new study in PLOS Biology explores the evolutionary history of gasdermins across metazoans, highlighting the conservation and divergence of gasdermin E. Gasdermin (GSDM) is a family of pore-forming proteins involved in various cellular processes such as cell death and inflammation. This Primer explores a PLOS Biology study of... Читать дальше...



Dismantling the tumoral cloak of self-protection

Plos.org 

by Mara B. Willis, Katherine Y. King

Tumors protect themselves from immune clearance by promoting extramedullary hematopoiesis. A new study in PLOS Biology provides insights into the mechanisms underlying this process, which may hold the key to disrupting generation of the immunosuppressive tumor microenvironment. The mechanisms by which tumors promote hematopoiesis outside the bone marrow have been the subject of intense interest. This Primer explores a new PLOS Biology study that provides... Читать дальше...

Best county to retire in every state

«Albany Democrat Herald» (democratherald.com) 

Stacker looks at the best county to retire in every state according to Niche's 2020 ratings. Some factors that determined the rankings include cost of living, crime rate, and population over the age of 65.

Colorado: Huerfano County

«Albany Democrat Herald» (democratherald.com) 

- Population: 6,787- National rank: 305The Spanish Peaks are a main attraction for active retirees who settle in Huerfano County. The county's cost of living is 21.4% lower than the U.S. average, making it a financially responsible choice for seniors…

Arkansas: Sharp County

«Albany Democrat Herald» (democratherald.com) 

- Population: 17,243- National rank: 41Tucked into the foothills of the Ozark Mountains, sparsely populated Sharp County became a retirement destination with the creation of Cherokee Village, the county's first retiree-focused community. Today, the county offers many outdoor recreational activities,…

The ‘coronation effect’: UK high street shelves being cleared of quiche and fizz - The Guardian

Top Stories (uk) - Google News (ru) 

  1. The ‘coronation effect’: UK high street shelves being cleared of quiche and fizz  The Guardian
  2. Brits jetting off on holiday for Coronation weekend - but will take decorations with them  Express
  3. Pembrokeshire pubs hoping for a right royal boost over coronation weekend  Western Telegraph
  4. King's Coronation to bring £450m boost to London  Evening Standard
  5. The costs of the coronation defy common sense - but a slimmed down monarchy could recoup the expense  inews
  6. View... Читать дальше...

Elephant Rumblings: A’s releasing new ticket deal

Athletics Nation 

Neville E. Guard-USA TODAY Sports

MLB news roundup

Happy Thursday, AN!

Yesterday the A’s announced a brand new and unique deal in an effort to bring fans back to the Coliseum:

A’s announce The A’s Summer Pass, which fans can purchase for $99 to watch 37 games between May 29-Aug. 23 in the Coliseum’s Oak Landing section. Pass includes Oak Landing T-shirt and discounts on premium seats, guest passes (up to four) and https://t.co/H2Aa9nX5ot purchases.

— Martín Gallegos (@MartinJGallegos) May 3... Читать дальше...





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