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Новости за 07.06.2023

Six Selected for Nebraska Athletics Hall of Fame

Nebraska Men's Basketball 

Five distinguished student-athletes and one legendary head coach make up the six individuals in the 2023 University of Nebraska Athletics Hall of Fame class, announced on Wednesday, June 7.

Office Building Rathausstraße 1 / Schuberth und Schuberth + Stadler Prenn + Ostertag

Archdaily.com 

Concept. The design won an open international architecture competition in 2013. The concept envisages the integration of an urban office building into a historical environment while taking a distinctive and contemporary approach. Although manifesting as a freestanding monolithic building, a perceptual grid interacts with its context. The development out of the analytical parameter-trio: depth, material, and detailing is most prominently reflected in the outer façade cladding.



Identifying potential sites for rainwater harvesting ponds (embung) in Indonesia’s semi-arid region using GIS-based MCA techniques and satellite rainfall data

Plos.org 

by Yulius Patrisius Kau Suni, Joko Sujono, Istiarto

People have used rainwater harvesting (RWH) technology for generations to a considerable extent in semi-arid and arid regions. In addition to meeting domestic needs, this technology can be utilized for agricultural purposes as well as soil and water conservation measures. Modeling the identification of the appropriate pond’s location therefore becomes crucial. This study employs a Geo Information System (GIS) based multi-criteria analysis (MCA) approach and satellite rainfall data... Читать дальше...

A short peptide LINC00665_18aa encoded by lncRNA LINC00665 suppresses the proliferation and migration of osteosarcoma cells through the regulation of the CREB1/RPS6KA3 interaction

Plos.org 

by Junwei Pan, Ming Liu, Xiaozong Duan, Dan Wang

Long noncoding RNAs (lncRNAs) encompass short open reading frames (sORFs) that can be translated into small peptides. Here, we investigated the encoding potential of lncRNA LINC00665 in osteosarcoma (OS) cells. Bioinformatic analyses were utilized to predict the lncRNAs with encoding potential in human U2OS cells. Protein expression was assessed by an immunoblotting or immunofluorescence method. Cell viability was assessed by cell counting Kit-8 (CCK-8). Читать дальше...

Trace quantification of GL-V9 and its glucuronide metabolites (5-O-glucuronide GL-V9) in Beagle dog plasma by UPLC–MS/MS and its application to a pharmacokinetic study

Plos.org 

by Xuefeng Zhang, Guanlan Liu, Zechun Sang, Qinglong Guo, Yuxin Zhou

GL-V9, a new synthetic flavonoid derived from wogonin, has shown beneficial biological functions. In this study, accurate and sensitive UPLC–MS/MS methods were developed and validated for the quantification of GL-V9 and its glucuronide metabolite (5-O-glucuronide GL-V9) in Beagle dog plasma. The chromatographic separation was performed on a C8 column (ACE Excel 5 C8 50×3.0 mm) using 0.1% formic acid and acetonitrile were used as mobile phase. Читать дальше...

Understanding how different surfaces and environmental biofilms found in food processing plants affect the spread of COVID-19

Plos.org 

by Austin Featherstone, Amanda Claire Brown, Sapna Chitlapilly Dass

Meat processing plants have been at the center of the SARS-CoV-2 pandemic, with a recent report citing 90% of US facilities having multiple outbreaks during 2020 and 2021. We explored the potential for biofilms to act as a reservoir in protecting, harboring, and dispersing SARS-CoV-2 throughout the meat processing facility environment. To do this, we used Murine Hepatitis Virus (MHV), as a surrogate for SARS-CoV-2, and meat... Читать дальше...





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