by Lucy Granat, Debbra Y. Knorr, Daniel C. Ranson, Emma L. Hamer, Ram Prosad Chakrabarty, Francesca Mattedi, Laura Fort-Aznar, Frank Hirth, Sean T. Sweeney, Alessio Vagnoni, Navdeep S. Chandel, Joseph M. Bateman
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by Huanfeng Hao, Li Song, Luoying Zhang
Sleep disruptions are quite common in psychological disorders, but the underlying mechanism remains obscure. Wolfram syndrome 1 (WS1) is an autosomal recessive disease mainly characterized by diabetes insipidus/mellitus, neurodegeneration and psychological disorders. It is caused by loss-of function mutations of the WOLFRAM SYNDROME 1 (WFS1) gene, which encodes an endoplasmic reticulum (ER)-resident transmembrane protein. Heterozygous mutation carriers... Читать дальше...
by Marina Athanasouli, Nermin Akduman, Waltraud Röseler, Penghieng Theam, Christian Rödelsperger
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by Marius Schneider, Alexander D. Bird, Albert Gidon, Jochen Triesch, Peter Jedlicka, Hermann Cuntz
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Photo by Rocky Widner/NBAE via Getty Images
The Lakers are playing Summer League basketball in Sacramento and Las Vegas. Here is a preview of every player’s potential and the role they might have with the team.
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Stan Szeto-USA TODAY Sports
MLB news roundup
Happy Monday, Athletics Nation!
Brent Rooker had himself a fine Sunday yesterday: he was named the A’s lone All-Star representative for 2023, and then hit his first home run since June 11. The former development was a bit of a surprise, as Rooker has been in a fairly deep slump since his red-hot start to the season. It seemed more likely that one of the A’s Rookie of the Year hopefuls, Ryan Noda or Esteury Ruiz would get the nod. Читать дальше...
Photo by Sam Hodde/Getty Images
Was the lack of rotation depth a motivator?
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As a French-American who grew up in France, I didn’t discover s’mores, that quintessential summer staple, until my family moved to the United States when I was 10. My American cousin showed me over a campfire how to assemble the treat, charring marshmallows and sandwiching them between graham crackers with a few…
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Grab a cocktail and get ready for the upcoming season of Bachelor in Paradise. Because as host Jesse Palmer put it, "It's wild, man." After all, not only will season nine be full of the usual...
Gillingham boss Neil Harris admits landing striker Alfie May would be a long-shot - amid reports of the club making an official offer to Cheltenham.
Club News
City's final away game of 2023 at Cambridge United has been brought forward to Friday, 22 December, 7.45pm.
Dana White gives Joe La Puma an exclusive look at his sneaker collection at UFC Headquarters in Las Vegas for another episode of Complex Closets and talks about
Mike Russell / Sounder at Heart
Elyse Bennett secured a dramatic comeback for OL Reign with a late goal against Louisville.
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Dynamic search ads appear to be phased out in favor of Performance Max campaigns. Here's what this transition might mean for advertisers.
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Farm owners and construction companies say the law, which started July 1, has already diminished their workforce.
Famed for its agave spirits, the legendary brand now encompasses Mexican cuisine and culture.
The Special Airworthiness Certificate lets the company advance flight testing. But in car form, the A5 has been driving around the San Francisco Bay area for months.
Whether you are going off-grid or safeguarding against blackouts, these beefy, WIRED-tested batteries can keep the lights on.
Global markets have kicked off the new quarter with solid gains from Asia to Europe (as previewed last week in "The Technical Overhang Is Done, July Starts With A Bullish Eruption") while US equity futures were in the green, with sentiment getting a boost thanks to Tesla and BYD climbing on record quarterly sales. Oil rallied as Saudi Arabia and Russia extended oil supply cuts. At 7:45am ET, S&P emini futures were flat, reversing an earlier rally, with trading activity subdued by today's half-day... Читать дальше...
Save $100 on this portable second monitor ahead of Prime Day.
Many business leaders want to do something important and valuable for their community, but it can often be a struggle to know where to start. Here are some rules I follow to find my best socially-conscious project ideas and put them into action.
Your location can determine what you can and can't see online.
Each lens of the Xreal Air AR glasses features a 1080p display that acts as a second monitor for any USB-C or HDMI device.
Body scan companies say they can diagnose cancer faster and that AI can make it cheaper. But there's a gap between that dream and the medical community's reality.
If you live in a high-rise or rent a rancher, installing rooftop solar might be impractical. But that doesn't mean you should give up on renewable energy.