Evaluation of first trimester maternal serum inhibin-A for preeclampsia screening
by Sakita Moungmaithong, Angel H. Kwan, Ada W. Tse, Natalie K. Wong, Michelle S. Lam, Jing Wang, Liona C. Poon, Daljit S. Sahota
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by Sakita Moungmaithong, Angel H. Kwan, Ada W. Tse, Natalie K. Wong, Michelle S. Lam, Jing Wang, Liona C. Poon, Daljit S. Sahota
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by Naoaki Rikihisa, Nobuyuki Mitsukawa, Hiroaki Rikhisa, Masayuki Nakao
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by Dipshay Avi Chand, Miriam Scadeng, Birger Victor Dieriks
Parkinson’s disease is characterised by a visual, preferential degeneration of the pigmented neurons in the substantia nigra. These neurons are pigmented by neuromelanin which decreases in Parkinson’s disease. Not much is known about NM as it is difficult to study and quantify, primarily due to its insolubility in most solvents except alkali. Neuromelanin quantification could progress the development of biomarkers for prodromal Parkinson’s... Читать дальше...
by Mohammad Howard-Azzeh, David L. Pearl, Terri L. O’Sullivan, Olaf Berke
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by Madison MacLeay, Georgios Banos, Francesc Xavier Donadeu
Early life performance traits in dairy cattle can have important influences on lifetime productivity. Poor health and fertility are of great economical and animal welfare concern. Circulating miRNAs have been linked to several livestock traits, including resistance to infection, fertility, and muscle development. This study aimed to identify circulating miRNAs associated with early life performance traits and aging in dairy cattle. Читать дальше...
by J. Henry Brems, Taylor Wagner, Julia Diamant, Andrea E. Davis, Ellen Wright Clayton
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by Rumiko Saito, Maina Otsu, Hidenori Kiyosawa, Gota Kawai
MSM/Ms mouse derived from the Japanese wild mouse has unique characteristics compared to the widely used C57BL/6 mouse. To examine the usefulness of the MSM/Ms mouse for the comparative genomic analysis, expression of small RNAs were analyzed by the large-scale sequence analysis for two strains of mouse, C57BL/6 and MSM/Ms. As a trial, expression of box C/D snoRNAs, which are the most abundant small RNAs in the cell, were analyzed. Читать дальше...
by Jordan D. Reinders, William J. Moar, Graham P. Head, Safeer Hassan, Lance J. Meinke
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by Samyah Siraj, Beheshta Momand, Ginny Brunton, Adam Dubrowski
IntroductionHealthcare providers in rural and remote (R&R) areas of Canada do not have the same access to skills development and maintenance opportunities as those in urban areas. Simulation-based education (SBE) is an optimal technique to allow healthcare providers to develop and maintain skills. However, SBE is currently limited mainly to universities or hospital-based research laboratories in urban areas. The purpose of this scoping review is to identify a model... Читать дальше...
by Pratibha Bhandari
BackgroundThe burden of non-communicable diseases is rapidly increasing among young adults in middle- and low-income countries. Asian migrant workers continue to be a significant contributor to South Korea’s economy; however, their cardiovascular health is neglected. We explored the prevalence of cardiovascular risk factors among Asian migrant workers in South Korea.
MethodsCross-sectional survey, anthropometric measurements, blood pressure measurements, and biochemical tests including triglyceride... Читать дальше...
by Erik Gengel, Zafrir Kuplik, Dror Angel, Eyal Heifetz
We propose a model for the structure formation of jellyfish swimming based on active Brownian particles. We address the phenomena of counter-current swimming, avoidance of turbulent flow regions and foraging. We motivate corresponding mechanisms from observations of jellyfish swarming reported in the literature and incorporate them into the generic modelling framework. The model characteristics is tested in three paradigmatic flow environments.
by Tiffany A. Walker, Alex D. Truong, Aerica Summers, Adviteeya N. Dixit, Felicia C. Goldstein, Ihab Hajjar, Melvin R. Echols, Matthew C. Woodruff, Erica D. Lee, Seema Tekwani, Kelley Carroll, Ignacio Sanz, F. Eun-Hyung Lee, Jenny E. Han
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by Yishuang Cui, Yanan Wu, Yingze Zhu, Wei Liu, Lanxiang Huang, Ziqian Hong, Mengshi Zhang, Xuan Zheng, Guogui Sun
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by Pei-Tsen Chen, Han-Wei Zhang, Zhi-Ren Tsai, Hsiao-Ching Peng, Yu-Shan Lin, Jeffrey J. P. Tsai, Chao-Wen Lin
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by Negar Alami, David C. Carter, Nisha V. Kwatra, Weihan Zhao, Linda Snodgrass, Ariel R. Porcalla, Cheri E. Klein, Daniel E. Cohen, Loretta Gallenberg, Melina Neenan, Robert A. Carr, Kennan C. Marsh, Dale J. Kempf
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by Chaohong Wang, Qing Sun, Jun Yan, Xinlei Liao, Sibo Long, Maike Zheng, Yun Zhang, Xinting Yang, Guangli Shi, Yan Zhao, Guirong Wang, Junhua Pan
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by Giacomo Stroffolini, Francesca Tamarozzi, Andrea Fittipaldo, Cristina Mazzi, Brandon Le, Susana Vaz Nery, Dora Buonfrate
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by Lauren G. Chukrallah, Sarah Potgieter, Lisa Chueh, Elizabeth M. Snyder
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by Daniel Scheller, Franziska Becker, Andrea Wimbert, Dominik Meggers, Stephan Pienkoß, Christian Twittenhoff, Lisa R. Knoke, Lars I. Leichert, Franz Narberhaus
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by Pengfei Li, Giovanni Messina, Christian F. Lehner
Spermatozoa in animal species are usually highly elongated cells with a long motile tail attached to a head that contains the haploid genome in a compact and often elongated nucleus. In Drosophila melanogaster, the nucleus is compacted two hundred-fold in volume during spermiogenesis and re-modeled into a needle that is thirty-fold longer than its diameter. Nuclear elongation is preceded by a striking relocalization of nuclear pore complexes (NPCs). Читать дальше...
by Yue Hao, Gábor Závodszky, Claudia Tersteeg, Mojtaba Barzegari, Alfons G. Hoekstra
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by Brittany Baur, Junha Shin, Jacob Schreiber, Shilu Zhang, Yi Zhang, Mohith Manjunath, Jun S. Song, William Stafford Noble, Sushmita Roy
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by Michael D. Nicholson, David Cheek, Tibor Antal
Stochastic models of sequential mutation acquisition are widely used to quantify cancer and bacterial evolution. Across manifold scenarios, recurrent research questions are: how many cells are there with n alterations, and how long will it take for these cells to appear. For exponentially growing populations, these questions have been tackled only in special cases so far. Here, within a multitype branching process framework, we consider a... Читать дальше...
by Juan Xie, Hyeongseon Jeon, Gang Xin, Qin Ma, Dongjun Chung
Single-cell RNA sequencing (scRNA-seq) data has been widely used for cell trajectory inference, with the assumption that cells with similar expression profiles share the same differentiation state. However, the inferred trajectory may not reveal clonal differentiation heterogeneity among T cell clones. Single-cell T cell receptor sequencing (scTCR-seq) data provides invaluable insights into the clonal relationship among cells, yet it lacks functional characteristics. Читать дальше...
A replicability crisis threatens computational science without shared code, data and methods from studies. A new replication agreement system can mitigate this crisis.