Researchers examine waste removal in cells, identifying segments of protein that play a role in RNA and DNA breakdown
If we don't take out the trash regularly, our homes become unpleasant and even a danger to our health. The same applies to our cells: If excess proteins and strands of genetic material aren't removed, the cell and ultimately the entire organism can fall ill. For example, scientists suspect there is a connection between Alzheimer's and mutations that cause defects in cellular garbage removal. What's more, tests with mice have shown that suppressing the breakdown of DNA and RNA can trigger serious autoimmune diseases.
