Lower Gastrointestinal Hemorrhage
This JAMA Clinical Guidelines Synopsis summarizes the 2023 American College of Gastroenterology guidelines on management of patients with acute lower gastrointestinal bleeding.
This JAMA Clinical Guidelines Synopsis summarizes the 2023 American College of Gastroenterology guidelines on management of patients with acute lower gastrointestinal bleeding.
In recent years, there has been a reevaluation of the upper gestational age limit recommended for administration of antenatal corticosteroids. Seven randomized clinical trials (RCTs) published between 2010 and 2022 have evaluated the effects of expanding the limit from 34 to 37 weeks’ gestation. The largest of these was the Antenatal Late Preterm Steroids (ALPS) trial published in 2016. In this trial, the administration of antenatal corticosteroids yielded a 20% relative reduction in the primary outcome (respiratory morbidity). Читать дальше...
In this narrative medicine essay, a retired physician describes the kindness, companionship, and skill of the hospice workers who helped his wife and him prepare for her death.
This JAMA Patient Page describes autism spectrum disorder (ASD) and its signs and symptoms, diagnosis, and therapy options.
This prospective cohort study compares the differences in time to mortality across sexual orientation in female nurses participating in the Nurses’ Health Study II.
In Reply Dr Jatoi suggests that a reduction in the incidence of ER-negative breast cancer over the past decades could have contributed to the decline in breast cancer mortality observed in SEER between 1975 and 2019. Indeed, a decline in cancer incidence can have a primary role in decline of cancer-specific mortality, as in the case of lung cancer. Similarly, a change in the composition of molecular subtypes among people diagnosed with incident breast cancer could affect mortality rates and even... Читать дальше...
To the Editor In their recent study, Dr Caswell-Jin and colleagues used 4 Cancer Intervention and Surveillance Modeling Network (CISNET) models and ascribe the 58% reduction in US breast cancer mortality between 1975 and 2019 to the use of effective treatments and screening. However, the CISNET models do not appear to account for the effect of declining estrogen receptor (ER)–negative breast cancer incidence on overall US breast cancer mortality rates. The US Surveillance, Epidemiology, and End Results... Читать дальше...
The family physician, after seeing a patient through the acute stages of an illness and subsequent convalescence, watched him until his ultimate return to work. The patient, usually stimulated by the daily needs of life on the farm and in the home, was chiefly interested in regaining his former place in his society. As he recuperated, he could make himself useful in many simple tasks. Gradually more difficult and strenuous skills would be regained. The relationship of the family physician to the... Читать дальше...
This JAMA Insights reviews the origin of APOL1 high-risk genetic variants, defines APOL1-mediated kidney disease, and discusses recommendations for screening and management.
This Medical News story discusses a clinical trial that tested symptom-guided exercise for patients with long COVID and postexertional malaise.
A new initiative, known as the Coronavirus Network or CoViNet, will bring together experts in human, animal, and environmental health to monitor known coronaviruses such as SARS-CoV-2 and Middle East respiratory syndrome coronavirus, or MERS-CoV, the World Health Organization (WHO) said in a recent statement. CoViNet will also aid in the early detection of novel coronaviruses. The network involves 36 laboratories across 21 countries, including the US Centers for Disease Control and Prevention.
Highly pathogenic avian influenza A(H5N1), also known as H5N1 bird flu, has been circulating among birds and mammals for the past few years. This March, US officials detected it in dairy cattle in several states. Later that month, a farm worker who was exposed to dairy cattle in Texas tested positive for H5N1 bird flu, the US Centers for Disease Control and Prevention (CDC) announced in a health alert.
More than one-third of climbers who were exposed to the low-pressure and low-oxygen environment of Mount Everest experienced a cardiac arrhythmia during their climb, a small study found. The data came from 41 healthy men who were, on average, in their mid-30s.
People with obesity who gained less than the recommended 5 kg to 9 kg of weight during pregnancy did not experience adverse outcomes, and neither did their children, according to data from about 15 800 pregnancies among people with obesity in Sweden.
People with high levels of blood glucose and triglycerides tended to have a greater risk of mental health conditions later than those who had normal levels of both, according to data from more than 211 000 participants in Sweden published in JAMA Network Open. Changes in some biomarkers were evident up to 20 years before participants were diagnosed.
Millions of people in the Americas have been infected with dengue and more than 1000 have died in the first 3 months of 2024, tripling the number of dengue cases that occurred in 2023 during the same period, according to a statement by the Pan American Health Organization (PAHO). Last year, more than 4.5 million cases of the mosquito-borne illness were reported in the region, which itself was a record. Still, the case fatality rate remained low, a trend that Jarbas Barbosa, MD, PhD, MS, the director of PAHO... Читать дальше...
Clinicians must now get written consent for medical students to conduct examinations or invasive procedures—such as breast, pelvic, prostate, and rectal checks—on patients for the trainees’ education, the US Department of Health and Human Services announced in a recent letter to teaching hospitals and medical schools. The guidance reinforces what is already standard care at many major institutions and aligns with several states’ current laws, according to the letter.
As of late March 2024, health officials in the US have recorded 143 cases of meningococcal disease, 101 of them caused by a strain of the bacteria Neisseria meningitidis known as sequence type (ST) 1466. The total number of cases of the disease represents a more than 75% increase over those reported at the same time last year, the US Centers for Disease Control and Prevention (CDC) announced.
People answering survey questions and filling out administrative forms from federal agencies will now answer 1 combined question about race and ethnicity and be able to select more than 1 option that represents their identity, the US Office of Management and Budget (OMB) announced in a recent statement. The OMB also added a new category for race and ethnicity: Middle Eastern or North African. The revisions are the first in almost 2 decades to the way the federal government characterizes race and ethnicity.
How people consume information is evolving. So is JAMA Medical News. This issue debuts JAMA Data Brief, a new department in the journal’s long-standing Medical News & Perspectives.
This Medical News article discusses a KFF poll about the public’s exposure to and beliefs about inaccurate health information, as well as media use and trust in sources.
The Original Investigation titled “Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials,” published on November 14, 2023, has been updated to add Christopher Horvat, MD, MHA, to the list of LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and REMAP-CAP Investigators. This article was corrected online.
AltruBio Raises $225M in Series B to Advance Ulcerative Colitis Candidate 5/21/2024
GSK’s Long-Acting Asthma Drug Hits Primary Endpoint in Phase III Trials 5/21/2024
Lilly Inks Potential $1.1B Radiopharma Deal with Aktis Oncology 5/21/2024