Retraction | Science Translational Medicine

On 5 May 2021, Science Translational Medicine published the Research Article “A subset of PARP inhibitors induces lethal telomere fusion in ALT-dependent tumor cells” by J. Mukherjee, A. Pandita, C. Kamalakar, T.-C. Johannessen, S. Ohba, Y. Tang, C. L. Dalle-Ore, R. Bjerkvig, and R. O. Pieper (

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). On 13 August 2022, the authors were made aware of concerns about the mechanistic data presented in the paper (parts of Figs. 3 to 7 and figs. S2, S5, and S6). The corresponding author, Russell O. Pieper, reported the matter to the appropriate office at his institution, the University of California–San Francisco, where it is currently being examined. In the interim, the corresponding author, with the agreement of all authors, has requested that the Research Article be retracted. Thus, Science Translational Medicine is retracting the paper in full.