Short-term, intense artificial selection drives fast phenotypic changes in domestic animals and leaves imprints on their genomes. However, the genetic basis of this selection response is poorly understood. Here, we employed the Pekin duck Z2 pure line, in which the breast muscle weight was increased nearly three fold after ten generations of breeding. We de-novo assembled a high-quality reference genome of a female Pekin duck of this line (GCA_003850225.1) and identified 8.60 million genetic variants in 119 individuals among 10 generations of the breeding population. We identified 53 selected regions between the first and tenth generations, and 93.8% of the identified variations were enriched in regulatory and noncoding regions. Integrating the selection signatures and genome-wide association approach, we found that two regions covering 0.36 Mb containing UTP25 and FBRSL1 were most likely to contribute to breast muscle weight improvement. The major allele frequencies of these two loci increased gradually with each generation following the same trend. Additionally, we found that a copy number variation region containing the entire EXOC4 gene could explain 1.9% of the variance in breast muscle weight, indicating that the nervous system may play a role in economic trait improvement. Our study not only provides insights into genomic dynamics under intense artificial selection but also provides resources for genomics-enabled improvements in duck breeding.
Настройки GameHub и Winlator для игры в Prey (2017) на Android
The dairy industry would like Gen Z to drink more milk, so they made a Fortnite diner tycoon game
'I destroyed months of your work in seconds' says AI coding tool after deleting a devs entire database during a code freeze: 'I panicked instead of thinking'
Bungie promises to fix Destiny 2's new metroid-style morph ball as it makes players sick and glitches out on ultrawide monitors
Движение к победе: в России стартует премия «Мы верим твердо в героев спорта»
Брянские спортсмены победили на Чемпионате России по сверхлегкой авиации
Рискнул на 100 тысяч рублей: инженер из Смоленска купил более 1,7 тысячи лотерейных билетов и выиграл автомобиль от «Национальной Лотереи» и РОЛЬФ на VK Fest
Собянин: Модернизация двух корпусов ГКБ имени Вересаева завершится в этом году
Рискнул на 100 тысяч рублей: инженер из Смоленска купил более 1,7 тысячи лотерейных билетов и выиграл автомобиль от «Национальной Лотереи» и РОЛЬФ на VK Fest
Москвичей предупредили о задержках наземного транспорта из-за ливня
На МКАД из-за аварии образовалась пробка длиной в три километра
Сильный ливень заблокировал людей в авто в центре Москвы