Making immunizations more effective: Exploring how adjuvants developed using computers boost vaccines

In addition to an antigen, many vaccines also contain substances, called adjuvants, which stimulate the immune system. By using computer-aided molecular design and machine learning, a Chinese research team has now developed two novel broad-spectrum adjuvants that can significantly amplify the immune response to vaccines. As reported in the journal Angewandte Chemie, they were able to enhance the effectiveness of immunization against certain forms of cancer in animal models.