Ni-Ti bimetallic system mediates enantioselective reductive aryl-benzylation of alkenes using free alcohols

Prof. Wang Xiaoming's group at the Shanghai Institute of Organic Chemistry, of the Chinese Academy of Sciences, has demonstrated the first nickel-titanium, bimetallic, system-catalyzed, asymmetric reductive aryl-benzylation of alkenes using benzyl alcohols, which afforded a series of biologically important benzene-fused cyclic compounds in good yields with high enantiomeric excess (ee) values. The work was published in Cell Reports Physical Science.