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2023

Unraveling the molecular basis of Dmc1 filament assembly in homologous recombination

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Homologous recombination (HR) is an important process that plays multiple crucial roles during meiosis, a type of cell cycle dedicated to sexual reproduction. During HR, homologous DNA molecules exchange their genetic material. During the meiotic prophase, DNA are clipped throughout the genome, forming numerous DNA double-strand breaks. Such DNA breaks attract homologous recombination enzymes, which promote pairing of homologous chromosomes.














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