Molecular biologists identify framework for understanding RNA editing in a disease-causing parasite

As molecular biologists at Boston University and as husband and wife, Ruslan Afasizhev and Inna Afasizheva have worked together for decades. Together, they have published dozens of papers on the mechanics of mitochondrial DNA and RNA in a single-celled, disease-causing parasite called Trypanosoma brucei. Now, years of breakthroughs have led to their latest paper published in Science, which provides a detailed look at a mystifying process called RNA editing and could potentially help treat a deadly disease.