Jessica Chastain says her friendship with Oscar Isaac has 'never quite been the same' since filming divorce drama 'Scenes from a Marriage'

• Jessica Chastain said she needed "a breather" from Oscar Isaac after filming "Scenes from a Marriage."
• The pair have been friends since college and starred in the HBO miniseries in 2021.
• However, Chastain said their friendship "has never quite been the same" since the show.

Jessica Chastain said that her close friendship with Oscar Isaac was greatly impacted by their last project together, "Scenes from A Marriage."

In the 2021 HBO miniseries, the actors, who have been friends since college, played a couple on the brink of divorce.

The pair have previously said that their friendship helped them on set, but in a new interview with Vanity Fair, Chastain said that their relationship "has never quite been the same" since filming the divorce drama.

"I mean, 'Scenes from a Marriage' was very tough," Chastain said.

"We're going to be okay, but after that, I was like, I need a little bit of a breather. There was so much 'I love you, I hate you' in that series," she added.

While promoting the series on the "Today" show in 2021, Chastain said that she and Isaac got under each other's skin while filming.

"We've been friends for more than half our lives and we know so much about each other," the 46-year-old actor said. "So we know how to make each other laugh without even saying anything. We can almost read each other's minds but also means we could hurt each other really strongly. In the scenes, we would know how to get to the other one."

Chastain added: "Sometimes before action, I would turn to Oscar, who plays the main caregiver of our child, and be like, 'The house looks really really messy. Why didn't you clean it?' And he was like, 'Grrrr.' We know how to dig in."

While their chemistry was strong in the series, fans were fixated on their real-life chemistry after a clip of Isaac kissing Chastain's arm on the red carpet at the Venice Film Festival went viral.

Asked about the viral red carpet moment, Chastain said that the moment was an accident. She was attempting to give Isaac a hug, while he had turned to give "a peck" on her elbow.

"Let me just say, though, this is a slow-motion video, and everybody is super sexy in slow motion," Chastain added. "We have all been locked in our houses for so long. When this video went viral, I was like, people just need to see people touch and hold each other."