Testing the limits of AlphaFold2's accuracy in predicting protein structure

Proteins, the workhorses of biology, are encoded by DNA sequences and are responsible for vital functions within cells. Since the first experimental measurement of a protein structure was made by John Kendrew in the 1950s, protein's ability to fold into complex three-dimensional structures has long been a subject of scientific fascination and importance. However, determining these structures experimentally has remained a formidable challenge for decades.