Researchers uncover a potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in the brain. Scientists have now found potential ways to interrupt this process by targeting 'sticky' sites along the long form of mutated tau, preventing the misfolding and spreading of the neurofibrillary tangles.