Maternal inheritance of Alzheimer's disease tied to increased risk of developing disease

Researchers analyzed 4,400 cognitively unimpaired adults with amyloid imaging, finding increased amyloid in those who reported that their mothers had symptoms of Alzheimer's disease (AD). Increased amyloid, a biomarker of AD, was also found in those with a history of the disease on both sides of their family and in those whose fathers had an early onset of symptoms. The study suggests that a person's maternal versus paternal family history could have a different impact on risk of accumulating amyloid in the brain.