Markets Right Now: Dow, S&P 500 set records; Nasdaq slips

The Dow Jones industrial average and the Standard & Poor's 500 index closed at record highs again but the Nasdaq composite fell, dragged down by declines in big technology names.

Eli Lilly plunged 11 percent after it said a potential treatment for Alzheimer's disease failed in a clinical trial.

The Dow Jones industrial average continues to set all-time highs even as other indexes slip in quiet pre-holiday trading on Wall Street.

Technology stocks are lower at midday Wednesday after HP released a weak profit forecast.

Drugmaker Eli Lilly plunged 12 percent after it said a potential treatment for Alzheimer's disease failed in a clinical trial.

Drugmaker Eli Lilly plunged 14 percent early Wednesday after it said a potential treatment for Alzheimer's disease failed in a clinical trial.