Chiefs blast 49ers, spoil Christian McCaffrey's debut

Patrick Mahomes passed for 423 yards and three touchdowns as the Kansas City Chiefs cruised to a 44-23 victory over the San Francisco 49ers on Sunday in Santa Clara, Calif.

Wide receiver Mecole Hardman scored his third touchdown of the game on a 3-yard run with 10:43 remaining to give the Chiefs a 35-23 lead. Fellow receiver JuJu Smith-Schuster closed the scoring with a 45-yard TD reception.

Leading 14-13 at halftime, t