Four Downs: What's Changed Since the 49ers-Seahawks Week 2 Matchup

Briana McDonald

The San Francisco 49ers hit the road this week and look for their seventh-consecutive win as they take on the Seattle Seahawks at Lumen Field on Amazon Prime Video's "Thursday Night Football." The Week 15 game marks the second contest of the 2022 season between the divisional rivals. In Week 2, the 49ers earned the first victory of the matchup, defeating Seattle 27-7.

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